

Retatrutide
Retatrutide (LY3437943) — Triple GLP-1 / GIP / glucagon receptor agonist
Research use only — intended for laboratory research. Not for human or veterinary use.
Retatrutide (LY3437943) is a first-in-class triple incretin receptor agonist designed by Eli Lilly. The molecule simultaneously engages the GLP-1, GIP, and glucagon receptors — adding glucagon-receptor activation to the dual GLP-1/GIP profile of tirzepatide. A C20 fatty diacid is conjugated to enable non-covalent albumin binding and extend the half-life to roughly 6 days. In SURMOUNT and Phase 2 obesity trials, retatrutide produced the largest body-weight reductions reported to date for any peptide agent, making it one of the most closely watched molecules in current metabolic research.
- Mol. weight
- 4731.43
- Purity
- ≥99.0%
- Form
- Lyophilized powder
- Storage
- −20°C, dry, dark
- CAS
- 2381089-83-2
- Formula
- C221H342N46O68
- Mol. weight
- 4731.43
- Purity
- ≥99.0%
- Form
- Lyophilized powder
- PubChem CID
- 171390338
Store lyophilized peptide at −20°C, protected from light and moisture. Once reconstituted with bacteriostatic water, store at 2–8°C and use within 28 days.
Retatrutide (LY3437943) is a first-in-class triple incretin receptor agonist designed by Eli Lilly. The molecule simultaneously engages the GLP-1, GIP, and glucagon receptors — adding glucagon-receptor activation to the dual GLP-1/GIP profile of tirzepatide. A C20 fatty diacid is conjugated to enable non-covalent albumin binding and extend the half-life to roughly 6 days. In SURMOUNT and Phase 2 obesity trials, retatrutide produced the largest body-weight reductions reported to date for any peptide agent, making it one of the most closely watched molecules in current metabolic research.
The RAC
standard
QuestionsQuestions
Each vial contains lyophilized peptide powder at the labeled dosage. No solvents, fillers, or preservatives.
Every batch is HPLC-tested. Certificate of Analysis (COA) and HPLC report are available on the product page.
Store the lyophilized peptide at −20°C, dry and dark. See the Storage tab for product-specific details.
United States only, in temperature-controlled packaging. 3–5 day standard or 1–2 day express.
No. All products are for laboratory and research use only (RUO) and are not intended for human or veterinary use.
Research use only. Not for human or veterinary use.


